Accelerating next-generation cell-based therapies.
UnRavEl immune-cancer cell interactions
The identification and selection of specific immune cells is the key to maximizing efficacy and minimizing the unwanted side effects of personalized cell-based immunotherapies.
The efficacy and specificity of therapeutics like CAR-T cells is determined by the interactions of tumor cells with T-cells and the surrounding matrix. Thus, a systematic characterization of these complex interactions serves as the basis for the accurate selection of therapeutic T-cell.
from CellCity in regards to immune cell therapy:
Monitor cells in a controlled, 3D microenvironment
Screen thousands of cells for multiple function or structure parameters
Pair T-cells with tumor cells to track their interactions
Expand selected T-cells in a growth-promoting environment
Use tumor cell killing and endpoint to select therapeutic T-cells
Work in a continuously sterile environment