CellCity System

A fully integrated system to track thousands of cells at a time and link their functional phenotypes of interest with their underlying genomic & transcriptional makeup.

TELL ME MORE

One Platform. Endless
Applications

Precision engineering makes the CellCity System a powerful and unique analysis tool that enables functional phenomics. Its plug-and-play format increases its portability and allows seamless integration into any automated inverted imaging microscope available in the laboratory or study routine.

CellCity Control Unit

The CellCity Control Unit automates all workflow steps essential for reliable cell culture and analysis and executes the experimental design through integrated control software.
Powerful and fast, traps thousands of cell-laden gel beads on a CellCity Array Chip within a few minutes
Light-weight, easily portable and designed for a quick plug-and-play setup
Brings microfluidic cell culture to any lab (intuitive user experience, automated flow control and priming, bubble-free operation)
Precision engineering delivers uniform perfusion to ensure homogeneous culture conditions
An integreated gas mixer allows direct connection to a 100% CO2 gas line or gas bottle

CellCity Incubator

The CellCity Incubator holds the CellCity Array Chip and maintains the relevant experimental conditions for long-term live-cell analysis.
A complete, miniature incubator (37°C, 5% CO₂). No need for any other environmental chamber.
Designed in a microtiter plate format to fit on your inverted microscope setup.
Controlled and optimized heating to work with low volumes and temperature sensitive samples
The CellCity Incubator can be easily moved to a cell culture hood for uninterrupted sterile conditions and handling

The Workflow in Six Steps

Step 1

SAMPLE

Use your conventional single-cell suspension as sample. Our CellCity Kits include high-grade hydrogel for cell encapsulation.

Step 2

CELL ENCAPSULATION:

Perform on-chip single-cell or cell-pair encapsulation according to your experimental plan. No prior microfluidic experience is required.

Step 3

GEL BEAD TRAPPING:

Immobilize thousands of cell-laden gel beads in microfluidic traps on the CellCity Array Chip within few minutes.

Step 4

CELL CULTURE & TIME LAPSE IMAGING:

Culture cells in physiologically relevant environmental conditions with the optional ability to stimulate cells. Track and monitor functional phenotypes by time-lapse imaging.