CellCity System

A fully integrated system to track thousands of cells at a time and link their functional phenotypes of interest with their underlying genomic & transcriptional makeup.
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CellCity Control Unit

  • The CellCity Control Unit automates all workflow steps essential for reliable cell culture and analysis and executes the experimental design through integrated control software.
  • Powerful and fast, traps thousands of cell-laden gel beads on a CellCity Array Chip within a few minutes
  • Light-weight, easily portable and designed for a quick plug-and-play setup
  • Brings microfluidic cell culture to any lab (intuitive user experience, automated flow control and priming, bubble-free operation)
  • Precision engineering delivers uniform perfusion to ensure homogeneous culture conditions
  • An integreated gas mixer allows direct connection to a 100% CO2 gas line or gas bottle

CellCity Incubator

  • The CellCity Incubator holds the CellCity Array Chip and maintains the relevant experimental conditions for long-term live-cell analysis.
  • A complete, miniature incubator (37°C, 5% CO₂). No need for any other environmental chamber.
  • Designed in a microtiter plate format to fit on your inverted microscope setup.
  • Controlled and optimized heating to work with low volumes and temperature sensitive samples
  • The CellCity Incubator can be easily moved to a cell culture hood for uninterrupted sterile conditions and handling

The Workflow in Six Steps

Some Examples

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Cell-Cell Interactions

 

Study cellular communication at single-cell resolution, e.g. during EMT in cancer metastasis.

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Cell Killing

 

Discover and explore serial killing events of individual CAR-T cells.

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Cell Division

 

Use cell division as a functional readout to reveal the role of cell proliferation in disease.

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PHAGOCYTOSIS

 

Visualize at single-cell resolution how, e.g. a macrophage phagocytoses a cancer cell.

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CO-POSITION TWO CELLS

Easily enclose two cells in one bead to monitor communication & regulation

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PRESERVE THE 3D SPACE AROUND CELLS

Easily control & maintain their chemical & cellular microenvironment

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LINK A CELL’S GENES & FUNCTION

Track reporter genes and other modifications of single cells upon response to stimuli

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USE YOUR EXISTING PROTOCOLS

No need to start from scratch. CellCity works with your current bioassays & imaging setup

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SEE PHENOTYPIC HETEROGENEITY IN POPULATIONS

Show phenotypic variation across time & space, and even track monoclonal cells

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YOUR IDEAS. YOUR CELLS. YOUR ASSAY

Answer questions with rare, eukaryotic, prokaryotic, primary, or other cells

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CellCity Kits

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CellCity Software Solutions