Unmask HeterogeneIty and resolve the layers of tumor microenvironment

Tumor cell heterogeneity poses a challenge to developing personalized cancer treatments. Within a tumor, cells are organized hierarchically, steered by stem-like cells which drive tumor growth, mediate metastasis, and contribute to treatment resistance resulting from genetic and epigenetic events that change the constitution and function of a tumor and the surrounding cells. Understanding that heterogeneity, especially based on the small number of circulating tumor cells (CTCs) found in liquid biopsies, will lead to breakthroughs enabled by our innovative functional phenomics platform.